Synthesis of naphtho[1,8-bc]pyran derivatives and related compounds through hydroxy group directed C-H bond cleavage under rhodium catalysis.

Abstract

The straightforward and efficient synthesis of naphtho[1,8-bc]pyran derivatives and related polycyclic compounds is achieved by the rhodium-catalyzed oxidative coupling of 1-naphthols or other phenolic and alcoholic substrates with alkynes. In these annulation reactions, the hydroxy groups effectively act as the key function for the regioselective C-H bond cleavage.

DOI: 10.1002/asia.200900639

Cite this paper

@article{Mochida2010SynthesisON, title={Synthesis of naphtho[1,8-bc]pyran derivatives and related compounds through hydroxy group directed C-H bond cleavage under rhodium catalysis.}, author={Satoshi Mochida and Masaki Shimizu and Koji Hirano and Tetsuya Satoh and Masahiro Miura}, journal={Chemistry, an Asian journal}, year={2010}, volume={5 4}, pages={847-51} }