Synthesis of multiple peptides on plastic pins.

@article{Rodda2001SynthesisOM,
  title={Synthesis of multiple peptides on plastic pins.},
  author={Stuart J Rodda},
  journal={Current protocols in protein science},
  year={2001},
  volume={Chapter 18},
  pages={Unit18.2}
}
Scanning protein sequences by bioassay for smaller bioactive peptide sequences requires a source of many peptides homologous with the parent protein sequence. This unit deals with one of the synthetic methods for making such sets of peptides. The strategy of the multiple peptide approach to biological scanning is discussed, along with the synthetic protocols, and the handling of peptides after synthesis, i.e., cleavage, preliminary purification, storage, and analysis. It is specific for the… CONTINUE READING