Synthesis of monofunctionalized gold nanoparticles by fmoc solid-phase reactions.

  title={Synthesis of monofunctionalized gold nanoparticles by fmoc solid-phase reactions.},
  author={K M Sung and David W. Mosley and Beau R. Peelle and Shuguang Zhang and Joseph Jacobson},
  journal={Journal of the American Chemical Society},
  volume={126 16},
In this communication, solid-phase reactions for the synthesis of Lys-monofunctionalized gold nanoparticles are described. A controlled and selective fabrication of linear nanoparticle arrays can be achieved through peptide linkage systems, and therefore it is essential to prepare Fmoc amino acid nanoparticle building blocks susceptible to Fmoc solid-phase peptide synthesis. Gold nanoparticles containing carboxylic acids (2) in the organic shell were covalently ligated to Lys on solid supports… 
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