Synthesis of functionalized dispiro[indoline-3,1$${^{\prime }}$$ ′ -cyclopentane-3$${^{\prime }}$$ ′ ,3$${^{\prime \prime }}$$ ″ -indolines] via cyclodimerization of 3-phenacylideneoxindolines with benzoylhydrazides and arylhydrazines

Abstract

The triethylamine-promoted domino cyclodimerization reaction of 3-phenacylideneoxindolines with benzohydrazides in acetonitrile afforded densely substituted dispiro[indoline-3,1$${^{\prime }}$$ ′ -cyclopentane-3$${^{\prime }}$$ ′ ,3$${^{\prime \prime }}$$ ″ -indolines] in good yields and with high diastereoselectivity. The similar domino reaction of 3… (More)
DOI: 10.1007/s11030-017-9786-z

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