Synthesis of electrophore-labeled oligonucleotides and characterization by matrix-assisted laser desorption/ionization mass spectrometry.

Abstract

Recent work to apply mass spectrometric methods to DNA analysis has led to the attachment of an electrophore to an oligonucleotide primer, with the purpose of investigating whether the advantages of electron capture ionization (increased ionization efficiency, reduced fragmentation) could be extended to larger molecules, such as Sanger sequence ladders. The… (More)

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@article{Britt1996SynthesisOE, title={Synthesis of electrophore-labeled oligonucleotides and characterization by matrix-assisted laser desorption/ionization mass spectrometry.}, author={Phillip F. Britt and Gina Hurst and Michelle V. Buchanan}, journal={Journal of mass spectrometry : JMS}, year={1996}, volume={31 6}, pages={661-8} }