Synthesis of d-labeled and unlabeled benzoyloxysuccinimides and application to quantitative analysis of peptides and a protein by isotope differential mass spectrometry.

Abstract

Benzoyloxysuccinimide and its d(5)-labeled version, which react with amino groups in the N-termini and lysine side chains in proteins, were synthesized and applied to quantitative analysis of peptides and a commercially available protein in combination with a MALDI mass spectrometer. 
DOI: 10.1016/j.bmcl.2011.05.090

Topics

Cite this paper

@article{ZabetMoghaddam2011SynthesisOD, title={Synthesis of d-labeled and unlabeled benzoyloxysuccinimides and application to quantitative analysis of peptides and a protein by isotope differential mass spectrometry.}, author={Masoud Zabet-Moghaddam and Aarif L. Shaikh and Lauren E Beste Jones and Satomi Niwayama}, journal={Bioorganic & medicinal chemistry letters}, year={2011}, volume={21 15}, pages={4629-32} }