Synthesis of cyclopentadiene-fused chromanones via one-pot multicomponent reactions.

@article{Ghandi2013SynthesisOC,
  title={Synthesis of cyclopentadiene-fused chromanones via one-pot multicomponent reactions.},
  author={M. Ghandi and A. Ghomi and M. Kubicki},
  journal={The Journal of organic chemistry},
  year={2013},
  volume={78 6},
  pages={
          2611-6
        }
}
  • M. Ghandi, A. Ghomi, M. Kubicki
  • Published 2013
  • Chemistry, Medicine
  • The Journal of organic chemistry
  • We have developed one-pot method for the synthesis of functionalized novel cyclopentadiene-fused chromanone scaffolds. A variety of 4-oxo-2,4-dihydrocyclopenta[c]chromene-1,2-dicarboxylates were obtained in moderate to good yields via condensation of 2-hydroxybenzaldehydes and ethyl acetoacetate with 1:1 acetylenecarboxylate-isocyanides in toluene. These reactions presumably proceed via reaction of the in situ generated 3-acetyl-2H-chromen-2-ones with acetylenecarboxylate-isocyanide… CONTINUE READING
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