Synthesis of carboxamides by LDA-catalyzed Haller-Bauer and Cannizzaro reactions.

Abstract

[reaction: see text] The first direct synthesis of N-alkylcarboxamides and N,N-dialkylcarboxamides by Haller-Bauer (HB) and Cannizzaro-type reactions has been realized. Lithium N,N-diisopropylamide (LDA) catalyst was successfully used in not only the HB reaction of benzylic ketones with lithium N-alkylamides to give the corresponding carboxamides and… (More)

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@article{Ishihara2004SynthesisOC, title={Synthesis of carboxamides by LDA-catalyzed Haller-Bauer and Cannizzaro reactions.}, author={Kazuaki Ishihara and Takayuki Yano}, journal={Organic letters}, year={2004}, volume={6 12}, pages={1983-6} }