Synthesis of an unusual polar glycopeptidolipid in glucose-limited culture of Mycobacterium smegmatis.

@article{Ojha2002SynthesisOA,
  title={Synthesis of an unusual polar glycopeptidolipid in glucose-limited culture of Mycobacterium smegmatis.},
  author={Anil Kr Ojha and Saaket Varma and Dipankar Chatterji},
  journal={Microbiology},
  year={2002},
  volume={148 Pt 10},
  pages={3039-48}
}
There has been a general understanding that Mycobacterium smegmatis produces only apolar glycopeptidolipid (GPL), similar in structure to serovar non-specific GPL of Mycobacterium avium. In this study, synthesis of polar GPL in carbon-starved M. smegmatis is reported. Mass spectrometric analysis suggests the polar GPL to be a hyperglycosylated species. The earlier structural studies of polar GPLs from M. avium have invariably shown the presence of an oligosaccharide appendage to D-allo-Thr… CONTINUE READING

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