Synthesis of an unspliced cytoplasmic message by an adenovirus 5 deletion mutant

@article{Carlock1981SynthesisOA,
  title={Synthesis of an unspliced cytoplasmic message by an adenovirus 5 deletion mutant},
  author={L. R. Carlock and Nicholas C. Jones},
  journal={Nature},
  year={1981},
  volume={294},
  pages={572-574}
}
Most genes in eukaryotic cells and their viruses contain non-coding intervening sequences (introns)1–5. These sequences are excised from each transcript during maturation of mRNA by a process known as RNA splicing. Although very little is known about the mechanism by which splicing occurs or its biological significance, several studies have suggested that… CONTINUE READING