Synthesis of an array of potential matrix metalloproteinase inhibitors using a sequence of polymer-supported reagents.

Abstract

Polymer-supported reagents and sequestering agents may be used to generate an array of variously substituted hydroxamic acid derivatives as potential inhibitors of matrix metalloproteinases without any chromatographic purification step. 

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Cite this paper

@article{Caldarelli1999SynthesisOA, title={Synthesis of an array of potential matrix metalloproteinase inhibitors using a sequence of polymer-supported reagents.}, author={Massimo Caldarelli and J. K. Habermann and Steven V Ley}, journal={Bioorganic & medicinal chemistry letters}, year={1999}, volume={9 14}, pages={2049-52} }