Synthesis of a novel linear polymer of a macrocyclic polyamine copper (II) complex and its interaction with plasmid DNA.

Abstract

The novel linear polymer of a macrocyclic polyamine copper (II) complex, which has many cyclen groups linked by epichlorohydrin, has been synthesized as a DNA cleavage agent. The structure of the polymer 3 was identified by 1HNMR and IR and its molecular weight was measured by GPC. The result of agarose gel electrophoresis assay showed that Cu-(II) complex… (More)
DOI: 10.1080/14756360802166806

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@article{Xiang2009SynthesisOA, title={Synthesis of a novel linear polymer of a macrocyclic polyamine copper (II) complex and its interaction with plasmid DNA.}, author={Yong-Zhe Xiang and Li-hong Zhou and Ning Jiang and Hong-hui Lin and Xiaoqi Yu}, journal={Journal of enzyme inhibition and medicinal chemistry}, year={2009}, volume={24 2}, pages={315-9} }