[Synthesis of a new neuromuscular blocking agent, pipecuronium bromide (Arduan)].

Abstract

A series of bisquaternary ammonio steroids having androstane skeleton have been prepared some of which possessed high neuromuscular blocking activity. One of the series 3 alpha, 17 beta-diacetoxy-2 beta, 16 beta-bis (4,4-dimethyl-1-piperazinyl)-5 alpha-androstane dibromide (19, pipecuronium bromide, ARDUAN) has proved to be a clinically useful agent of long… (More)

Topics

Cite this paper

@article{Tuba1992SynthesisOA, title={[Synthesis of a new neuromuscular blocking agent, pipecuronium bromide (Arduan)].}, author={Zolt{\'a}an Tuba and S{\'a}ndor Mah{\'o}}, journal={Acta pharmaceutica Hungarica}, year={1992}, volume={62 3}, pages={73-81} }