Synthesis of a Heptapeptide and Its Application in the Detection of Mercury(II) Ion

@article{Huiyun2017SynthesisOA,
  title={Synthesis of a Heptapeptide and Its Application in the Detection of Mercury(II) Ion},
  author={Feng Huiyun and Gao Lei and YE Xinhui and W. Lei and Xue Zechun and Kong Jinming and Li Lianzhi},
  journal={Chemical Research in Chinese Universities},
  year={2017},
  volume={33},
  pages={155-159}
}
A new heptapeptide, Cys-Pro-Gly-Cys-Pro-Gly-Cys-CONH2(P7), was prepared via Fmoc solid-phase peptide synthesis, purified by high performance liquid chromatography(HPLC) and characterized by mass spectro-metry(MS). The interactions of P7 with metal ions were also investigated by spectroscopy and the results show that P7 has highly selective binding affinity to Hg(II). Based on this specific character, a simple, rapid and sensitive detection method for Hg(II) was developed. When the mixture… Expand
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