Synthesis of a Heptapeptide and Its Application in the Detection of Mercury(II) Ion

  title={Synthesis of a Heptapeptide and Its Application in the Detection of Mercury(II) Ion},
  author={Feng Huiyun and Gao Lei and YE Xinhui and W. Lei and Xue Zechun and Kong Jinming and Li Lianzhi},
  journal={Chemical Research in Chinese Universities},
A new heptapeptide, Cys-Pro-Gly-Cys-Pro-Gly-Cys-CONH2(P7), was prepared via Fmoc solid-phase peptide synthesis, purified by high performance liquid chromatography(HPLC) and characterized by mass spectro-metry(MS). The interactions of P7 with metal ions were also investigated by spectroscopy and the results show that P7 has highly selective binding affinity to Hg(II). Based on this specific character, a simple, rapid and sensitive detection method for Hg(II) was developed. When the mixture… Expand
4 Citations
Dansyl-peptide dual-functional fluorescent chemosensor for Hg2+ and biothiols
Abstract A new dansyl-peptide dual-functional fluorescent chemosensor (D-ECEW-NH2, D-P4) was developed via Fmoc solid phase peptide synthesis (SPPS), which displayed an excellent selectivity and highExpand
Multifunctional peptide-based fluorescent chemosensor for detection of Hg2+ , Cu2+ and S2- ions.
New possibilities for using a short fluorescent peptide sensor for multifunctional detection, especially for anions are given. Expand
Ultrasensitive mercury ion and biothiol detection based on Dansyl-His-Pro-Gly-Asp-NH2 fluorescent sensor.
A new fluorescent chemical sensor Dansyl-His-Pro-Gly-Asp-NH2 (D-P4) was synthesized for the determination of Hg2+. Expand
A Highly Selective and Sensitive Peptide-Based Fluorescent Ratio Sensor for Ag+
Results showed that the fluorescence ratio sensor based on dansyl-peptide is an excellent Ag + sensor under neutral condition and displays good practicality for Ag + detection in river water samples without performing tedious sample pretreatment, as well as for silver chloride detection. Expand


Ratiometric and turn-on monitoring for heavy and transition metal ions in aqueous solution with a fluorescent peptide sensor.
The fluorescent enhancement, binding affinity, and detection limit of the peptide probe for HTM ions were described and were lower than the EPA's drinking water maximum contaminant levels (MCL). Expand
Ferrocene-based small molecules for dual-channel sensing of heavy- and transition-metal cations.
The synthesis, electrochemical, optical, and cation-sensing properties of ferrocene-pentakis(phenylthio)benzene dyads, linked through a putative cation -binding 2-azadiene bridge, are presented and the experimental data and conclusions about the ion-s sensing properties are supported by DFT calculations. Expand
Rosamine-based fluorescent chemosensor for selective detection of silver(I) in an aqueous solution.
The synthesis and photophysical properties of a rosamine-based fluorescent chemosensor, RosAg, for detecting Ag ion in an aqueous solution are described and it is suggested that aniline nitrogen is likely to be associated with the Ag(+) center in the solution state. Expand
A rapid and sensitive p-benzoquinone-mediated bioassay for determination of heavy metal toxicity in water.
The presented bioassay not only provides a good foundation for further toxicity tests using E. coli, but also has the potential for expanding the technique to utilize other bacteria with complementary toxicity responses, thereby allowing use of the bioassays in a wide range of applications. Expand
A fluorescent and colorimetric probe based on isatin-appended rhodamine for the detection of Hg2+
A new fluorescent probe for the detection of Hg2+ was designed and synthesized via attaching N-methylisatin to rhodamine B hydrazide through an imine linkage. In an ethanol-Tris buffer medium, theExpand
Luminescent iridium phenanthroline crown ether complex for the detection of silver(I) ions in aqueous media.
While 1 is a highly selective chemosensor for Ag+ in the presence of many metal ions, there is a strong interference of Hg2+ that may restrict its practical use. Expand
A near-infrared-fluorescent chemodosimeter for mercuric ion based on an expanded porphyrin.
An expanded porphyrin [26]hexaphyrin( was exploited as a fluorescent chemodosimeter for Ag + ions with high sensitivity and selectivity via near-infrared luminescence above 900 nm, aExpand
Flexible colorimetric detection of mercuric ion by simply mixing nanoparticles and oligopeptides.
A colorimetric approach based on organic chromophoric probes based on Au nanopar-ticles (NPs) has drawn much attention and is particularly attractive for point-of-use applications. Expand
Development of a visual optode sensor for onsite determination of Hg(II)
Abstract A color changeable cellulose triacetate (CTA) membrane-based optode has been developed for the highly selective and sensitive determination of Hg(II) ions in aqueous solutions. The sensingExpand
A ratiometric fluorescent sensor for Ag(I) with high selectivity and sensitivity.
A bicyclic cycloadduct 1 bearing a pyrenyl moiety has been synthesized and investigated as a ratiometric fluorescent sensor for AgI, which exhibits a strong intensity enhancement of the pyrene excimer emission at the expense of the emission of monomeric pyrene. Expand