Synthesis of Some Novel Bis[1, 2, 4]triazolo[3, 4-b][1, 3, 4]thiadiazine Derivatives for Antimicrobial Evaluation.

@article{Reddy2011SynthesisOS,
  title={Synthesis of Some Novel Bis[1, 2, 4]triazolo[3, 4-b][1, 3, 4]thiadiazine Derivatives for Antimicrobial Evaluation.},
  author={Cherkupally Sanjeeva Reddy and Dasari Chandrasekhar Rao and Vookanti Yakub and Adki Nagaraj},
  journal={Acta chimica Slovenica},
  year={2011},
  volume={58 3},
  pages={582-9}
}
A new series of novel bis[1, 2, 4]triazolo[3, 4-b][1, 3, 4]thiadiazines 7a-j has been synthesized by the reaction of [5, 5'-methylenebis(3-methylbenzofuran-7, 5-diyl)]bis[(4-amino-5-thioxo-4, 5-dihydro-1H-1, 2, 4-triazol-3-yl)methanone] (6) with a variety of phenacyl bromides in ethanol under reflux for 6 h. All the newly synthesized compounds were tested for in vitro activity against certain strains of bacteria such as Escherichia coli, Klebsiella pneumoniae, Shigella dysenteriae and Shigella… CONTINUE READING