Synthesis of Resveratrol Derivatives and In Vitro Screening for Potential Cancer Chemopreventive Activities.

@article{Orsini2016SynthesisOR,
  title={Synthesis of Resveratrol Derivatives and In Vitro Screening for Potential Cancer Chemopreventive Activities.},
  author={Fulvia Orsini and Luisella Verotta and Karin Klimo and Clarissa Gerh{\"a}user},
  journal={Archiv der Pharmazie},
  year={2016},
  volume={349 6},
  pages={414-27}
}
New resveratrol (trans-3,4',5-trihydroxystilbene) analogs were synthesized and screened for their in vitro cancer chemopreventive potential using various bioassays relevant for the prevention of carcinogenesis in humans: two assays to detect modulators of carcinogen metabolism (Cyp1A inhibition; determination of NAD(P)H/quinone reductase (QR) activity… CONTINUE READING