Synthesis of Pyridine and Spiropyridine Derivatives Derived from 2-aminoprop- 1-ene-1,1,3-tricarbonitrile Together with their c-Met Kinase and Antiproliferative Evaluations.

@article{Mohareb2018SynthesisOP,
  title={Synthesis of Pyridine and Spiropyridine Derivatives Derived from 2-aminoprop- 1-ene-1,1,3-tricarbonitrile Together with their c-Met Kinase and Antiproliferative Evaluations.},
  author={Rafat Milad Mohareb and Amr S. Abouzied and Nermeen Saeed Abbas},
  journal={Anti-cancer agents in medicinal chemistry},
  year={2018},
  volume={17 14},
  pages={1951-1962}
}
BACKGROUND Among a wide range of pyridines, 3-cyanopyridines acquired a special attention due to their wide range of pharmacological activities especially the therapeutic activities. Many pharmacological drugs containing the pyridine nucleus were known in the market. OBJECTIVE The aim of this work was to synthesize target molecules not only possess anti… CONTINUE READING