Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies.


Copper(I)-catalyzed azide-alkyne cycloaddition, or CuAAC click chemistry, is an efficient method for bioconjugation aiming at chemical and biological applications. Herein, we demonstrate how the CuAAC method can provide novel phospholipid-protein conjugates with a high potential for the diagnostics and therapy of autoimmune conditions. In doing this, we… (More)
DOI: 10.3390/molecules200610253


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