Synthesis of Phosphoester Compounds Using Lactic Acid for Encapsulation of Paclitaxel.

BACKGROUND/AIM In the use of paclitaxel, side-effects caused by itself or solubilizing agents have become a major obstacle. In this study we aimed to synthesize biocompatible and degradable compounds for micelles to be used as carriers for paclitaxel. MATERIALS AND METHODS Methoxypolyethylene glycol-lactate was obtained from methyl lactate and… CONTINUE READING