Synthesis of New 1 , 3 , 7 , 8-tetrasubstituted Xanthenes Analogue

  title={Synthesis of New 1 , 3 , 7 , 8-tetrasubstituted Xanthenes Analogue},
  author={Loay K. Abdulrahman and Maiada M. Al-mousilly and Tagreed S. Al-Halaibeh and Khalid M. Al-Azzawii},
  • Loay K. Abdulrahman, Maiada M. Al-mousilly, +1 author Khalid M. Al-Azzawii
  • Published 2012
ABSTRACT Theophylline, a methyl xanthenes compound, is known as an efficient bronchodilator drug, having also anti-inflammatory and immunomodulatory effects. In order to improve its pharmacological profile and to reduce also the serious side effects that appear at high concentrations, new 1, 3, 7, 8-tetrasubstituted theophylline derivatives have been… CONTINUE READING