Synthesis of N-aryl substituted p-toluenesulphonamides via nickel catalyzed amidation reaction and their antibacterial, antifungal and antioxidant activities evaluation.

@article{Izuchukwu2018SynthesisON,
  title={Synthesis of N-aryl substituted p-toluenesulphonamides via nickel catalyzed amidation reaction and their antibacterial, antifungal and antioxidant activities evaluation.},
  author={Ugwuja Daniel Izuchukwu and Okoro Uchechukwu Chris and Ugwu David Izuchukwu},
  journal={Pakistan journal of pharmaceutical sciences},
  year={2018},
  volume={31 4},
  pages={
          1209-1216
        }
}
In present study nickel catalyzed synthesis of N-(aryl) substituted p-toluene sulphonamides is reported. The intermediate 4-methylbenzenesulphonamide (2) was obtained by the reaction between p-toluene sulphonyl chloride and ammonium hydroxide. Various readily available aryl halides (3a-e) Substituted p-toluene sulphonamides (4a-e) were obtained by coupling 4-methylbenezenesulphonamide (2) with via Buchwald-Hartwig cross-coupling reaction. Chemical structures of synthesized compounds were… CONTINUE READING
1
Twitter Mention

References

Publications referenced by this paper.
SHOWING 1-10 OF 33 REFERENCES

Synthesis and Antibacterial Evaluation of some Novel Imidazole and Benzimidazole Sulphonamides, Molecules

Nassir N. AI-Mohammed, Yatimah Alias, Zanariah Abdullah, Raied
  • 2013

Synthesis and Antimicrobial Activity of some New Macrocyclic Bis - Sulphonamide and Disulphides

H Eshaghi, M Rahimizadeh, +4 authors Kihanyan
  • Eur . J . Chem .
  • 2011

Synthesis and Antimicrobial Activity of some New Macrocyclic Bis-Sulphonamide and Disulphides, Eur

H Eshaghi, M Rahimizadeh, +4 authors Kihanyan
  • J. Chem., 2(1): 47-45.
  • 2011

Prolongation of the Shelf Life of Fruits and Flowers, Material from Biocenter Klein FlottBek

Bergmann Ralph
  • University of Hamburg, Accessed Online on 4 December,
  • 2010

Similar Papers

Loading similar papers…