Synthesis of C2-chiral bifunctionalised spin labels and their application to troponin C.

Abstract

An enantiomeric pair of C2-chiral bifunctionalised spin labels having a pyrrolidine nitroxide moiety, whose configurations were determined by X-ray crystal diffraction analysis, was prepared and applied to troponin C whose binding mode of double disulfide linkage was proved by EPR spectroscopy.

Cite this paper

@article{Chatani2005SynthesisOC, title={Synthesis of C2-chiral bifunctionalised spin labels and their application to troponin C.}, author={Shunsuke Chatani and Motoyoshi Nakamura and Hidenobu Akahane and Naoki Kohyama and Masayasu Taki and Toshiaki Arata and Yukio Yamamoto}, journal={Chemical communications}, year={2005}, volume={14}, pages={1880-2} }