Synthesis of 3-substituted pyrazolo[1,5-a]-pyridines by electrophilic reactions

@article{Miki1994SynthesisO3,
  title={Synthesis of 3-substituted pyrazolo[1,5-a]-pyridines by electrophilic reactions},
  author={Yasuyoshi Miki and Sanae Yagi and Hiroko Hachiken and Masazumi. Ikeda},
  journal={Heterocycles},
  year={1994},
  volume={38},
  pages={1881-1887}
}
Reactions of pyrazolo[1,5-a]pyridines with Eschenmoser's salt, activa- ted alkenes and alkynes, and chlorosulfonyl isocyanate provided general routes to 3-substituted pyrazolo[1,5-a]pyridines such as 3-dimethylami- nomethyl-and 3-(2-nitroethyl)pyrazolo[1,5-a]pyridines, 1-phenyl-3-(py- razolo[1,5-a]pyrid-3-yl)-2-propen-1-ones, 4-(pyrazolo[1,5-a]pyrid-3-yl) -3-buten-2-one, pyrazolo[1,5-a]pyridine-3-carboxamide, and pyrazolo [1,5-a]pyridine-3-carbonitrile 
9 Citations
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