Synthesis of 3-keto-quinolines from enaminones, anilines and DMSO: Transition metal free one pot cascade

@inproceedings{Wakade2019SynthesisO3,
  title={Synthesis of 3-keto-quinolines from enaminones, anilines and DMSO: Transition metal free one pot cascade},
  author={Sandip Balasaheb Wakade and Dharmendra Kumar Tiwari and Mandalaparthi Phanindrudu and Pushpendra},
  year={2019}
}
Abstract An efficient and transition metal-free approach for the synthesis of functionalized 3-ketoquinolines from readily available anilines, enaminones and DMSO in the presence of K 2 S 2 O 8 has been conducted. This one pot tandem reaction proceeds through [3+2+1] cycloaddition reaction involving DMSO, enaminones and amines. In this environmental benign approach, DMSO acts as both a one carbon source and the solvent. A broad range of variously substituted amines and enaminones are… CONTINUE READING

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