Synthesis of 3-O-Acetylbetulinic And Betulonic Aldehydes According to Svern and the Pharmacological Activity of Related Oximes

Abstract

As is known, triterpenoids of the lupane group exhibit a wide spectrum of biological activity [1 – 3]. Of considerable interest are lupane aldehydes, the derivatives of which were reported to possess anti-HIV and antimelanoma properties [4, 5]. Previously, compounds of the lupane group were oxidized by reagents containing Cr(VI): CrO3 in acetone [6… (More)
DOI: 10.1023/A:1020824506140

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@article{Flekhter2004SynthesisO3, title={Synthesis of 3-O-Acetylbetulinic And Betulonic Aldehydes According to Svern and the Pharmacological Activity of Related Oximes}, author={O. B. Flekhter and O. Yu. Ashavina and Eugene I Boreko and L. T. Karachurina and Natalia I Pavlova and Natalie N Kabal'nova and Olga V Savinova and F. Z. Galin and Svetlana N. Nikolaeva and Felix S Zarudii and Lia A Baltina and Genrikh A Tolstikov}, journal={Pharmaceutical Chemistry Journal}, year={2004}, volume={36}, pages={303-306} }