Synthesis of 2-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)-3-((dimethylamino)methyl)camphor organocatalysts.


In a stereo-divergent synthesis, three novel camphor-derived bifunctional thiourea organocatalysts 7-9 have been prepared in five steps starting from (+)-camphor. In addition, borneol-derived bifunctional thiourea organocatalysts 19/19' have been prepared in three steps from (1S)-(+)-camphorquinone. Novel organocatalysts 7-9, 19/19' have been evaluated in a… (More)
DOI: 10.1002/chir.22035


Cite this paper

@article{Groelj2012SynthesisO2, title={Synthesis of 2-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)-3-((dimethylamino)methyl)camphor organocatalysts.}, author={Uro{\vs} Gro{\vs}elj and Sebastjan Ri{\vc}ko and Jurij Svete and Branko Stanovnik}, journal={Chirality}, year={2012}, volume={24 5}, pages={412-9} }