Synthesis, crystal structure and antiproliferative evaluation of some new substituted benzothiazoles and styrylbenzothiazoles.

Abstract

The multistep synthesis of a series of new substituted-benzothiazoles as hydrochloride or quaternary salts is described. 6-Amidino substituted 2-aminobenzothiazoles (5, 6), N-methyl-2-(4-cyanostyryl)benzothiazolium iodide (8), cyano-substituted-2-styrylbenzothiazoles (9-11) and amidino and bis-amidino-substituted 2-styrylbenzothiazoles (12-17) were prepared… (More)

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Cite this paper

@article{aleta2004SynthesisCS, title={Synthesis, crystal structure and antiproliferative evaluation of some new substituted benzothiazoles and styrylbenzothiazoles.}, author={Irena {\'C}aleta and Mira Grdi{\vs}a and Draginja Mrvos-Sermek and Mario Cetina and Vesna Trali{\'c}-Kulenovi{\'c} and Kre{\vs}imir Paveli{\'c} and Grace Karminski-Zamola}, journal={Farmaco}, year={2004}, volume={59 4}, pages={297-305} }