Synthesis, conformational analysis and biological activities of lanthionine analogs of a cell adhesion modulator.

Abstract

Cell adhesion is critical for many biological processes, such as hemostasis, wound healing, tumor metastasis and inflammation. Integrins are important mediators of cell adhesion. The integrin alpha4beta1, also known as VLA-4, is a cell surface receptor involved in inflammation. A cyclic peptide, 1-FCA-Arg-c[Cys-Asp-Thz-Cys]-OH, is a potent antagonist to VLA… (More)

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Cite this paper

@article{Li2001SynthesisCA, title={Synthesis, conformational analysis and biological activities of lanthionine analogs of a cell adhesion modulator.}, author={H y Li and Xiaoyin Sara Jiang and Max Lawrence Goodman}, journal={Journal of peptide science : an official publication of the European Peptide Society}, year={2001}, volume={7 2}, pages={82-91} }