Synthesis, antimicrobial, and anti-inflammatory activities of acetamido pyrrolyl azoles

Abstract

The acetamido pyrrolyl oxazoles/thiazoles/imidazoles were prepared and tested for their antimicrobial and anti-inflammatory activities. The nitro substituted acetamido pyrrolyl thiazole (11f) and pyrrolyl imidazole (12f) exhibited promising antibacterial activity against K. pneumoniae. The compound 12f showed good antifungal activity against P. chrysogenum. The methoxy acetamido pyrrolyl oxazole (10c) displayed potential anti-inflammatory activity.

DOI: 10.1007/s00044-017-1801-5

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Cite this paper

@article{Sowmya2017SynthesisAA, title={Synthesis, antimicrobial, and anti-inflammatory activities of acetamido pyrrolyl azoles}, author={Donthamsetty V. Sowmya and Shaik Sharafuddin Basha and Palampalli Uma Maheswari Devi and Yerraguravagari Lavanyalatha and Adivireddy Padmaja and Venkatapuram Padmavathi}, journal={Medicinal Chemistry Research}, year={2017}, volume={26}, pages={1010-1021} }