Synthesis and supramolecular assemblies of bipolar archaeal glycolipid analogues containing a cis-1,3-disubstituted cyclopentane ring.

@article{Brard2004SynthesisAS,
  title={Synthesis and supramolecular assemblies of bipolar archaeal glycolipid analogues containing a cis-1,3-disubstituted cyclopentane ring.},
  author={Micka{\"e}lle Brard and Walter Richter and Thierry Benvegnu and Daniel Plusquellec},
  journal={Journal of the American Chemical Society},
  year={2004},
  volume={126 32},
  pages={10003-12}
}
Unsymmetrical archaeal tetraether glycolipid analogues 1-2 incorporating a 1,3-disubstituted cyclopentane ring into the bridging chain have been synthesized. The cyclopentane has been introduced with a totally controlled cis configuration, either into the middle of the aliphatic chain or at three methylene groups from the glycerol unit linked to the bulkier disaccharide residue. Freeze-fracture and cryotransmission electron microscopy experiments clearly demonstrated unprecedented glycolipid… CONTINUE READING