Synthesis and structural revision of a brominated sesquiterpenoid, aldingenin C.

@article{Takahashi2014SynthesisAS,
  title={Synthesis and structural revision of a brominated sesquiterpenoid, aldingenin C.},
  author={Shunya Takahashi and M. Yasuda and T. Nakamura and K. Hatano and K. Matsuoka and H. Koshino},
  journal={The Journal of organic chemistry},
  year={2014},
  volume={79 19},
  pages={
          9373-80
        }
}
  • Shunya Takahashi, M. Yasuda, +3 authors H. Koshino
  • Published 2014
  • Medicine, Chemistry
  • The Journal of organic chemistry
  • This paper describes a short step synthesis of the proposed structure for aldingenin C from trans-limonene oxide. The tetrahydropyran-fused 2-oxabicyclo[3.2.2]nonane skeleton as the structural feature was constructed by an intramolecular epoxide-opening reaction and a brominative cyclization. The spectral data of the synthetic compound did not match those of the natural product reported. Re-examination of the reported NMR data using new CAST/CNMR Structure Elucidator suggests that the structure… CONTINUE READING
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