Synthesis and structural elucidation of novel benzothiazole derivatives as anti-tubercular agents: In-silico screening for possible target identification.

@article{Venugopala2018SynthesisAS,
  title={Synthesis and structural elucidation of novel benzothiazole derivatives as anti-tubercular agents: In-silico screening for possible target identification.},
  author={Katharigatta N Venugopala and Sandeep Chandrashekharappa and Melendhran Pillay and Subhrajyoti Bhandary and Mahmoud Kandeel and Fawzi M. Mahomoodally and Mohamed Abdelhamed Morsy and Deepak Chopra and Bandar Essa Aldhubiab and Mahesh Veerabhadra Attimarad and Osama Ibrahim Alwassil and Sree N Harsha and Koleka Mlisana},
  journal={Medicinal chemistry (Shariqah (United Arab Emirates))},
  year={2018}
}
BACKGROUND Benzothiazole derivatives are known for anti-TB properties. Based on the known antiTB benzothiazole pharmacophore, in the present study, we described the synthesis, structural elucidation, and anti-tubercular screening of a series of novel benzothiazole (BNTZ) derivatives (BNTZ 1-7 and BNTZ 8-13). OBJECTIVE Development of benzothiazole based… CONTINUE READING