Synthesis and separation of diastereomers of uridine 2',3'-cyclic boranophosphate.

@article{He2001SynthesisAS,
  title={Synthesis and separation of diastereomers of uridine 2',3'-cyclic boranophosphate.},
  author={Kaizhang He and Barbara Shaw},
  journal={Bioorganic & medicinal chemistry letters},
  year={2001},
  volume={11 5},
  pages={615-7}
}
The first boron-containing 2',3'-cyclic phosphate-modified analogue, uridine 2',3'-cyclic boranophosphate (2',3'-cyclic-UMPB), was synthesized. 5'-O-Protected uridine was cyclophosphorylated by diphenyl H-phosphonate to yield uridine 2',3'-cyclic H-phosphonate, which upon silylation followed by boronation and subsequent acid treatment gave 2',3'-cyclic-UMPB… CONTINUE READING