Synthesis and release studies of shikonin-containing microcapsules prepared by the solvent evaporation method.

@article{Assimopoulou2003SynthesisAR,
  title={Synthesis and release studies of shikonin-containing microcapsules prepared by the solvent evaporation method.},
  author={Andreana N. Assimopoulou and Vassilios P. Papageorgiou and Costas Kiparissides},
  journal={Journal of microencapsulation},
  year={2003},
  volume={20 5},
  pages={
          581-96
        }
}
Microcapsules, containing the pharmaceutical substance shikonin, were prepared by the solvent evaporation method in order to enhance shikonin stability (reduce photo-oxidation, polymerization), decrease its hydrophobicity and control its release rate. The effect of various parameters, such as type of polymer, type and concentration of surfactant, solvent volume and mastic gum (Pistacia lentiscus resin) content/concentration as core additive, on the characteristics of the produced microcapsules… CONTINUE READING