Synthesis and radiation-protection and antihypoxia properties of 3-hydroxypiperidin-4-one derivatives

Abstract

Cinnamoyl oxiranes (Ia-h) are condensed by known methods with methyland benzylamines to give the C(3)-stereoisomeric, 6-aryl-substi tuted 3e-hydroxypiperidin-4-ones (II-IX) [2] and 3a-hydroxypiperidin-4-ones (X-XIV) [3] (see Table 1). Their physical constants and spectral data correspond with l i terature values [2, 3]. Thus, the PMR spectra for the… (More)
DOI: 10.1007/BF00778367

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1 Figure or Table

Cite this paper

@article{Ilyuchenok2004SynthesisAR, title={Synthesis and radiation-protection and antihypoxia properties of 3-hydroxypiperidin-4-one derivatives}, author={T. Yu. Il'yuchenok and M. N. Romanchak and Inna Tishchenko and L. S. Stanishevskii and L. M. Frigidova and Yu. V. Zav'yalov and K. S. Shadurskii and A. S. Zakharevskii and A. V. Miklevich}, journal={Pharmaceutical Chemistry Journal}, year={2004}, volume={12}, pages={219-221} }