Synthesis and properties of NBD-n-acylcholines, fluorescent analogs of acetylcholine.

Abstract

We have synthesized a homologous series of fluorescent analogs of acetylcholine, N-7-(4-nitrobenzo-2-oxa-1,3-diazolyl)-omega-amino-n-alkanoic acid beta (N,N,N-trialkylammonium) ethylesters (NBD-n-acylcholines) and report here on their physiological and biochemical properties. All NBD-n-acylcholines trimethylated at the cholinergic nitrogen are agonists of… (More)

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@article{Meyers1983SynthesisAP, title={Synthesis and properties of NBD-n-acylcholines, fluorescent analogs of acetylcholine.}, author={H W Bud Meyers and R J{\"u}rss and Howard Brenner and Gabriele Fels and H. Prinz and Herbert Hans Watzke and Alfred Maelicke}, journal={European journal of biochemistry}, year={1983}, volume={137 3}, pages={399-404} }