Synthesis and preliminary antihyperlipidaemic activities evaluation of andrographolide derivatives.

@article{Wang2012SynthesisAP,
  title={Synthesis and preliminary antihyperlipidaemic activities evaluation of andrographolide derivatives.},
  author={Bin Wang and Chunlei Tang and Yaodan Han and Ruzhou Guo and Hai Qian and Wen-long Huang},
  journal={Medicinal chemistry (Shariqah (United Arab Emirates))},
  year={2012},
  volume={8 2},
  pages={293-8}
}
Recent studies indicated that andrographolide was a potential antihyperlipidaemic therapeutic agent. In the paper, the synthesis of a series of andrographolide derivatives was described and their antihyperlipidaemic activities were evaluated in vivo. As compared with TG, TC, HDL-C and LDL-C concentrations, some of the derivatives exhibited better… CONTINUE READING