Synthesis and photobiological study of a novel chlorin photosensitizer BCPD-18MA for photodynamic therapy.

@article{Zhang2011SynthesisAP,
  title={Synthesis and photobiological study of a novel chlorin photosensitizer BCPD-18MA for photodynamic therapy.},
  author={Jialiang Zhang and Li Deng and Jianzhong Yao and Peng Gu and Feng Yang and Xiu Yun Wang and Wei Liu and Yingying Zhang and Xingfa Ke and Xiaolong Jing and Jianming Chen},
  journal={Bioorganic \& medicinal chemistry},
  year={2011},
  volume={19 18},
  pages={
          5520-8
        }
}
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Chlorin p6-Based Water-Soluble Amino Acid Derivatives as Potent Photosensitizers for Photodynamic Therapy.

Aspartylchlorin p6 dimethylester (7b) represents a promising photosensitizer for PDT applications because of its strong absorption in the phototherapeutic window, relatively high singlet oxygen quantum yield, highest dark toxicity/phototoxicity ratio, good water solubility, and excellent in vivo PDT antitumor efficacy.

Benzochloroporphyrin derivative photosensitizer-mediated photodynamic therapy for Ewing sarcoma.

Synthesis and pharmacological evaluation of chlorin derivatives for photodynamic therapy of cholangiocarcinoma.

Antitumor effect of photodynamic therapy with a novel targeted photosensitizer on cervical carcinoma.

The results suggested that apoptosis was the primary mode of HeLa cell death induced by Ps I-PDT and has potential as an alternative treatment modality for cervical cancer.

A novel chlorin-PEG-folate conjugate with higher water solubility, lower cytotoxicity, better tumor targeting and photodynamic activity.

Novel dual-mode antitumor chlorin-based derivatives as potent photosensitizers and histone deacetylase inhibitors for photodynamic therapy and chemotherapy.

Synthesis and in vitro phototoxicity of novel π-extension derivatives of chlorin e6

The enhanced cellular uptake and reactive oxygen species (ROS) production of modified chlorins were found to be responsible for their increased in vitro phototoxicity.

Design and synthesis of novel water-soluble amino acid derivatives of chlorin p6 ethers as photosensitizer

Amino acid derivatives of pyropheophorbide-a ethers as photosensitizer: Synthesis and photodynamic activity

Current status of liposomal porphyrinoid photosensitizers.

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