Synthesis and photobiological study of a novel chlorin photosensitizer BCPD-18MA for photodynamic therapy.

@article{Zhang2011SynthesisAP,
  title={Synthesis and photobiological study of a novel chlorin photosensitizer BCPD-18MA for photodynamic therapy.},
  author={Jialiang Zhang and Li Deng and Jianzhong Yao and Peng Gu and Feng Yang and Xiu Yun Wang and Wei Liu and Yingying Zhang and Xingfa Ke and Xiaolong Jing and Jianming Chen},
  journal={Bioorganic \& medicinal chemistry},
  year={2011},
  volume={19 18},
  pages={
          5520-8
        }
}

Chlorin p6-Based Water-Soluble Amino Acid Derivatives as Potent Photosensitizers for Photodynamic Therapy.

Aspartylchlorin p6 dimethylester (7b) represents a promising photosensitizer for PDT applications because of its strong absorption in the phototherapeutic window, relatively high singlet oxygen quantum yield, highest dark toxicity/phototoxicity ratio, good water solubility, and excellent in vivo PDT antitumor efficacy.

Benzochloroporphyrin derivative photosensitizer-mediated photodynamic therapy for Ewing sarcoma.

Antitumor effect of photodynamic therapy with a novel targeted photosensitizer on cervical carcinoma.

The results suggested that apoptosis was the primary mode of HeLa cell death induced by Ps I-PDT and has potential as an alternative treatment modality for cervical cancer.

Synthesis and in vitro phototoxicity of novel π-extension derivatives of chlorin e6

The enhanced cellular uptake and reactive oxygen species (ROS) production of modified chlorins were found to be responsible for their increased in vitro phototoxicity.

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