Synthesis and pharmacology of two new histamine receptor antagonists related to ranitidine.

Abstract

Pyridyl and 1,6-dihydropyridyl ranitidine analogues 1 and 2 were obtained by applying an improved modification of ranitidine synthesis. Compound 1 shows a selective H2 antagonistic activity while compound 2 is a non-selective histamine antagonist.

Cite this paper

@article{Navarro1995SynthesisAP, title={Synthesis and pharmacology of two new histamine receptor antagonists related to ranitidine.}, author={Jaime Navarro and Jos{\'e} Felipe Almeida and Josefa Anaya and Joaqu{\'i}n R. Mor{\'a}n and M C Grande and Mar{\'i}a Cristina Caballero and Berenice Palacios and Mar{\'i}a Jos{\'e} Montero and Luis San Rom{\'a}n}, journal={Die Pharmazie}, year={1995}, volume={50 1}, pages={12-5} }