Synthesis and pharmacologic activity of amides of γ-aminobutyric acid


Earlier we had prepared a series of esters of y-aminobutyric acid (I) and examined their neurotropic activity [i]. We showed that esterification of I with alcohols containing lipophilic radicals forms esters with marked neurotropic activity and the ability to increase the life span of animals under conditions of hypoxia; the most active of these compounds… (More)
DOI: 10.1007/BF00777396