Synthesis and luminescence spectral characterization of long-lifetime lipid metal-ligand probes.

@article{Li1997SynthesisAL,
  title={Synthesis and luminescence spectral characterization of long-lifetime lipid metal-ligand probes.},
  author={Lina Li and Henryk Szmacinski and Joseph R. Lakowicz},
  journal={Analytical biochemistry},
  year={1997},
  volume={244 1},
  pages={80-5}
}
We synthesized phospholipid analogues of phosphatidyl ethanolamine which contains a ruthenium metal-ligand complex (MLC) covalently bound to the amino group. Two analogues were synthesized, containing either one (Ru-PE) or two (Ru-PE2) lipid molecules covalently linked to the MLC by the amino group of the lipid. These MLC-lipid probes display intensity decay times from 682 to 357 ns, depending on temperature. Importantly, the luminescence MLC groups display polarized emission, enabling their… CONTINUE READING