Synthesis and in vitro cytotoxicity study of 3-(1H-indol-3-yl)-1,3-diphenylpropan-1-ones

Abstract

A series of 3-(1H-indol-3-yl)-1,3-diphenylpropan-1-ones 3a–l were synthesized in good to excellent yield by Michael addition of indole 1 with α,β-unsaturated ketones 2a–l in presence of indium(III) sulphate (20 mol%). The structure of the title compounds were established by 1H NMR, 13C NMR, mass and elemental analysis. All the synthesized compounds were… (More)
DOI: 10.1007/s00044-013-0875-y

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