Synthesis and in vitro anti-tubercular evaluation of 1,2,3-triazole tethered β-lactam-ferrocene and β-lactam-ferrocenylchalcone chimeric scaffolds.

Abstract

Twenty different triazoles were prepared to probe the anti-tubercular structure-activity relationships (SAR) within the β-lactam-ferrocene-triazole conjugate family. The compounds have been synthesized by copper-catalyzed "click chemistry". In vitro anti-tubercular activity was determined for each compound but the synthesized hybrids failed to inhibit… (More)
DOI: 10.1039/c2dt30514c

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@article{Kumar2012SynthesisAI, title={Synthesis and in vitro anti-tubercular evaluation of 1,2,3-triazole tethered β-lactam-ferrocene and β-lactam-ferrocenylchalcone chimeric scaffolds.}, author={K. Shiva Kumar and Pardeep Singh and Laurent Kremer and Yann Gu{\'e}rardel and Christophe Biot and Vipan Kumar}, journal={Dalton transactions}, year={2012}, volume={41 19}, pages={5778-81} }