Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae.

@article{Strahl2007SynthesisAF,
  title={Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae.},
  author={Thomas Strahl and Jeremy Thorner},
  journal={Biochimica et biophysica acta},
  year={2007},
  volume={1771 3},
  pages={
          353-404
        }
}
It is now well appreciated that derivatives of phosphatidylinositol (PtdIns) are key regulators of many cellular processes in eukaryotes. Of particular interest are phosphoinositides (mono- and polyphosphorylated adducts to the inositol ring in PtdIns), which are located at the cytoplasmic face of cellular membranes. Phosphoinositides serve both a structural and a signaling role via their recruitment of proteins that contain phosphoinositide-binding domains. Phosphoinositides also have a role… CONTINUE READING

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