Synthesis and experimental study of a dextran-ferrite-based magnetically driven nanopreparation as an MRI contrast agent for tumor-feeding vessels

@article{Brusentsov2011SynthesisAE,
  title={Synthesis and experimental study of a dextran-ferrite-based magnetically driven nanopreparation as an MRI contrast agent for tumor-feeding vessels},
  author={N. A. Brusentsov and Yu. A. Pirogov and A. A. Uchevatkin and V. A. Polyanskii and T. N. Brusentsova and Andrey V. Ivanov},
  journal={Pharmaceutical Chemistry Journal},
  year={2011},
  volume={45},
  pages={84-87}
}
Dextran-ferrite (DF) nanoparticles were synthesized and the related DF sol was successfully tested in vivo as a negative contrast agent for enhancing early magnetic resonance imaging (MRI) detection of tumor, capsule, and tumor-feeding vessels. Intravenous injection of DF in combination with Magnevist and subsequent T2,T 2 * -weighted 3D scanning gave… CONTINUE READING