Synthesis and evaluation of triazole-linked poly(ε-caprolactone)-graft-poly(2-methyl-2-oxazoline) copolymers as potential drug carriers.

@article{Guillerm2012SynthesisAE,
  title={Synthesis and evaluation of triazole-linked poly(ε-caprolactone)-graft-poly(2-methyl-2-oxazoline) copolymers as potential drug carriers.},
  author={Brieuc Guillerm and Vincent Darcos and Vincent Lapinte and Sophie Monge and Jean Coudane and J. R. Robin},
  journal={Chemical communications},
  year={2012},
  volume={48 23},
  pages={2879-81}
}
Well-defined graft copolymers were obtained using a copper-catalysed azide-alkyne Huisgen's cycloaddition click reaction from both biocompatible and non-toxic poly(ε-caprolactone) and poly(2-methyl-2-oxazoline) homopolymers. Resulting amphiphilic copolymers proved to form micelles that could be used as potential drug carriers.