Synthesis and evaluation of platinum complexes with potential antitumor activity

Abstract

A novel series of platinum (II) complexes was synthesized and the complexes were evaluated for their in vitro cytotoxicity against four human cancer cells lines. Five platinum complexes showed activity against at least one tumor cell line. Complexes 3 and 6 were promising, being active, at micromolar concentrations, against all the assayed tumor cell lines… (More)

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Cite this paper

@inproceedings{Lima2017SynthesisAE, title={Synthesis and evaluation of platinum complexes with potential antitumor activity}, author={Rachel Silviano Brand{\~a}o Correa Lima and Marcelino Freire and Maria Bet{\^a}nia de Freitas Marques and Elaine Maria de Souza and Renata Barbosa de Oliveira and Ricardo Alves}, year={2017} }