Synthesis and cytotoxicity of 2,3-enopyranosyl C-linked conjugates of genistein.

Abstract

A series of glycoconjugates, derivatives of genistein containing a C-glycosylated carbohydrate moiety, were synthesized and their anticancer activity was tested in vitro in the human cell lines HCT 116 and DU 145. The target compounds 15-17 were synthesized by treating ω-bromoalkyl C-glycosides derived from L-rhamnal (1) with a tetrabutylammonium salt of… (More)
DOI: 10.3390/molecules19067072

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@article{Szeja2014SynthesisAC, title={Synthesis and cytotoxicity of 2,3-enopyranosyl C-linked conjugates of genistein.}, author={Wiesław Szeja and Grzegorz Grynkiewicz and Tadeusz Bieg and Piotr Świerk and Anna Byczek and Katarzyna Papaj and Radosław Kitel and Aleksandra Rusin}, journal={Molecules}, year={2014}, volume={19 6}, pages={7072-93} }