Synthesis and cytotoxic activity of certain benzothiazole derivatives against human MCF-7 cancer cell line.


A new series of benzothiazole has been synthesized as cytotoxic agents. The new derivatives were tested for their cytotoxic activity toward the human breast cancer MCF-7 cell line against cisplatin as the reference drug. Many derivatives revealed good cytotoxic effect, whereas four of them, 4, 5c, 5d, and 6b, were more potent than cisplatin, with IC50… (More)
DOI: 10.1111/cbdd.12879


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