Synthesis and chromatography-free purification of PNA-PEO conjugates for the functionalisation of gold sensors.

@article{Dettin2012SynthesisAC,
  title={Synthesis and chromatography-free purification of PNA-PEO conjugates for the functionalisation of gold sensors.},
  author={Monica Dettin and Davide Silvestri and Roberta Danesin and Erica Cretaio and Gianluca Picariello and Elisabetta Casarin and Agnese Sonato and Filippo Romanato and Margherita Morpurgo},
  journal={Molecules},
  year={2012},
  volume={17 9},
  pages={11026-45}
}
Peptide Nucleic Acids (PNAs) linked to high molecular weight (MW) poly(ethylene oxide) (PEO) derivatives could be useful conjugates for the direct functionalisation of gold surfaces dedicated to Surface Plasmon Resonance (SPR)-based DNA sensing. However their use is hampered by the difficulty to obtain them through a convenient and economical route. In this… CONTINUE READING